Gastroenterología

Categorías: ,

Descripción

EUROPLUS liver (monkey) and gliadin (GAF-3X) antigen

  • Detection of antibodies against endomysium and gliadin.
  • Indications: gluten-sensitive enteropathy (coeliac disease, non-tropical sprue), Duhring’s herpetiform dermatitis.
  • Initial dilution 1 : 10; conjugate class anti-human IgA or IgG, primate absorbed, FITC-labelled.
  • Autoantibodies against endomysium react with many types of tissue, e.g. primate oesophagus. The most suitable substrate, however, is primate liver: in the case of a positive sample, filamentous linings of the intralobular sinusoids react.
  • With the gliadin (GAF-3X)-coated BIOCHIP, antibodies against gliadin can be analysed in one and the same test procedure.
  • Both anti-endomysium antibodies and antibodies against gliadin (class IgA) are reliable serological markers for an active gluten-sensitive enteropathy. Therefore, their determination can in many cases replace endoscopy and biopsy.
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