Initial dilution 1 : 10; conjugate class anti-human IgA or IgG, primate absorbed, FITC-labelled.
Autoantibodies against endomysium react with many types of tissue, e.g. primate oesophagus. The most suitable substrate, however, is primate liver: in the case of a positive sample, filamentous linings of the intralobular sinusoids react.
With the gliadin (GAF-3X)-coated BIOCHIP, antibodies against gliadin can be analysed in one and the same test procedure.
Both anti-endomysium antibodies and antibodies against gliadin (class IgA) are reliable serological markers for an active gluten-sensitive enteropathy. Therefore, their determination can in many cases replace endoscopy and biopsy.